Friday, December 27, 2013

test

Google Busts Yet Another Link Network: Anglo Rank

Dec 6, 2013 at 3:20pm
Google’s head of search spam, Matt Cutts, just confirmed on Twitter that Google has targeted another “private link network” – this one is named Anglo Rank.
Matt’s tweet was pretty direct, he wrote:
“There are absolutely NO footprints linking the websites together” Oh, Anglo Rank.
That is a quote directly from Anglo Rank’s marketing material, and a dig from Cutts suggesting that indeed, Google was able to spot sites in the network.
In response, Search Engine Land’s editor-in-chief Matt McGee suggested on Twitter that those in the network were likely to find that it was “torched.” Cutts responded by saying “messages can take a few days to show up in [Google Webmaster Tools], so timing of when to post can be tricky to predict.”
In other words — yes, Cutts confirmed that Anglo Rank was penalized, and that those involved with it were getting penalty notifications, and since those were finally starting to appear in Google Webmaster Tools, Cutts felt it was OK to finally go more public with a tweet.
Over the past year or so, Google has been going after link networks at greater speeds. Here are some of the reports we have on those stories over a year or so:
Cutts did say that Anglo Rank is not the only link network targeted in this effort. He responded to me that Google has “been rolling up a few” link networks in this specific target.
So if you get a message in Google Webmaster Tools about paid links in the next day or so, it may be related to this update.

Wednesday, May 1, 2013

[節稅方法] 上班族如何節稅


更多報稅技巧

所謂薪資所得包含上班族在職務或工作上取得之各種薪資收入,包括:薪金(底薪)、俸給(加班費)、工資、津貼(伙食津貼、職務津貼等)、歲費、獎金(績效獎金、三節獎金、全勤獎金等)、紅利及各種補助費。其中有些依規定可免列入個人所得課稅,趕快一起來檢視你的薪資扣繳憑單數字有無異常!


•    加班費
上班族依勞動基準法第 24 條規定「延長工作時間之工資」及第 32 條規定「每月平日延長工作總時數」限度內支領之加班費 (每日不超過12小時,每月不超過46小時),可免納所得稅 。但若因天災、事變或突發事件而延長的工作時間,則不受每月46小時的免稅時數限制。

•    伙食津貼
一般營利事業按月給付的伙食費與加班誤餐費在1800元範圍內,免視為員工之薪資所得。但超過部分就必須列入薪資所得計算。

Thursday, April 11, 2013

Peptide|鉅生Peptide合成



Peptide簡介


所謂的Peptide胜肽,其實就是由幾個氨基酸所結合而成的物質。基本上,分子量比蛋白質小,結構也比蛋白質簡單,因此,經由皮膚可以有效吸收。

常在使用保養品化妝品的人可能都有聽過Peptide這個詞,近年推出有美白活肌抗皺功效的保養品通常都宣成含有Peptide抗老化成分。而Peptide為什麼可以抗老化呢?下面我們就來簡單的為你說明:


Peptide功用:



Peptide(胜肽)的種類有很多主要分為


二胜肽:化妝品中常見的多半發現有抗敏、抗發炎、抗氧化的功能

三胜肽:常用的有藍銅胜肽 ( Copper-peptide ),為生長因子,能加速修護傷口,增加上皮組織再生,保護角質層,恢復肌膚年輕。

四胜肽:常見的四胜肽為年輕因子激活肽 ( Rigin ),為合成的免疫球蛋白,可以對抗老化、保護肌膚對抗紫外線對皮膚的傷害、防止發炎、延緩老化。

五胜肽:最常見的五胜肽 ( Matrixyl ), 可以刺激膠原蛋白的增生,減少皺紋,增加肌膚彈性與光澤。

六胜肽:化妝品界最常見的是類肉毒六胜肽( Argireline ),具有與肉毒桿菌相同的機轉,卻沒有肉毒桿菌的副作用。最近科學家由不同序列,有了令人興奮的發現:美白六胜肽,它可以抑制黑色素刺激荷爾蒙的形成,阻止黑色素的產生,對美白領域是嶄新的突破。


Peptide合成


鉅生生技的peptide synthesis(氨基酸合成)服務



交貨期: 扣除序列合成時間,需要約三個月

所有詳細資訊歡迎來店洽詢。






地址:台北市中山區南京東路三段189號8樓

電話:(02)27604952

網址:http://www.angene.tidi.tw/

Peptide資訊:http://twhere.1111.com.tw/vShop.aspx?sNo=12016
 

Wednesday, April 3, 2013

[Share] Scaling Up Peptide Drugs - Apr 1, 2013 (Vol. 7, No. 33)

The peptides sector of the biotechnology industry has ridden out the global economic challenges of recent years largely on the strength of existing and advancing peptide projects in pharma pipelines and continuing demand for peptides in a range of research applications.
Companies are expressing optimism that the increase in requests for proposals (RFPs) they began to see toward the end of 2012 will continue and return the sector to the double-digit, 10–12% growth rates it enjoyed 4–5 years ago.

Friday, March 29, 2013

Tools for peptides


PESTfind - Identification of PEST regions at EMBnet Austria
HLA_Bind - Prediction of MHC type I (HLA) peptide binding
PEPVAC - Prediction of supertypic MHC binders
RANKPEP - Prediction of peptide MHC binding
SYFPEITHI - Prediction of MHC type I and II peptide binding
ProtScale - Amino acid scale representation (Hydrophobicity, other conformational parameters, etc.)
Drawhca - Draw an HCA (Hydrophobic Cluster Analysis) plot of a protein sequence
Protein Colourer - Tool for coloring your amino acid sequence
Three To One - Tool to convert a three-letter coded amino acid sequence to single letter code
Colorseq - Tool to highlight (in red) a selected set of residues in a protein sequen
Protein identification and characterization
Identification and characterization with peptide mass fingerprinting data
Aldente - Identify proteins with peptide mass fingerprinting data. A new, fast and powerful tool that takes advantage of Hough transformation for spectra recalibration and outlier exclusion
FindMod - Predict potential protein post-translational modifications and potential single amino acid substitutions in peptides. Experimentally measured peptide masses are compared with the theoretical peptides calculated from a specified Swiss-Prot entry or from a user-entered sequence, and mass differences are used to better characterize the protein of interest.
FindPept - Identify peptides that result from unspecific cleavage of proteins from their experimental masses, taking into account artefactual chemical modifications, post-translational modifications (PTM) and protease autolytic cleavage
GlycoMod - Predict possible oligosaccharide structures that occur on proteins from their experimentally determined masses (can be used for free or derivatized oligosaccharides and for glycopeptides)


The Peptide Bond



The peptide bond links the carbonyl carbon of one amino acid residue to the amino nitrogen of another. Learn the characteristics of the peptide bond and how to interpret Ramachandran plots in this webcast.

Peptide bond formation - Biofundamentals



A short introduction into peptide bond formation and polypeptide structure

http://trade.1111.com.tw/web/peptide